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Proviron Rus Bio is the brand name for the orally applicable androgen and DHT (dihydrotestosterone) derivative called Mesterolone. Roughly 5% of testosterone undergoes 5-alpha reduction to form the potent androgen DHT, which is a sex hormone and androgen hormone. DHT plays a major role in the formation of the male genitals, and, in adults, it acts as the primary androgen in the prostate and hair follicles. Proviron is almost as pure a DHT steroid as you will find out there. With DHT compounds such as Proviron Rus Bio, you need not worry about any estrogen aromatization.
Studies have shown Proviron Rus Bio is effective for depression, anxiety and to boost lack of sex drive. Hence, it would make sense that those with bipolar, unipolar, and dysthymia would benefit from this hormone. It's generally prescribed by doctors to men with low libido. In addition, it's a precursor to full TRT (testosterone replacement therapy).
Proviron Rus Bio was popularized years ago as an anti-estrogen because it is has a high affinity to bind to the aromatase enzyme, so anabolic steroid (AS) users could use it to serve as their AI (aromatase inhibitor) replacement. Bodybuilders were using it during post cycle therapy (PCT); unfortunately, studies have shown proviron does suppress LH (luteinizing hormone) – in some cases. As a result, high proviron dosage can prevent the pituitary gland from recovering after a steroid cycle. Some users insist proviron does not suppress the HPTA when used in PCT or during a bridge; however, this is up for debate. As a side note, some studies support long term use of proviron at high dosages without serious suppression. The science supports proviron use for PCT but not in every case.
Now that we have aromasin, arimidex, and letrozole, proviron has become obsolete when it comes to anti-estrogen usage. We know that the true aromatase inhibitors (AI) are safe to use during post cycle therapy, and will not suppress your HPTA. Though, proviron shouldn't either.
In this respect, it doesn't mean proviron does not have its uses on cycle when using an aromatizing compound such as dianabol, testosterone, nandrolones, or equipoise. In fact, a user can expect to have a harder look, more vascularity, and less puffiness when stacking proviron with a wet compound.
Another benefit of proviron is that it binds very well to SHBG (sex hormone binding globulin), which is the hormone responsible for reducing free testosterone circulating in the body. This is probably the reason why some use proviron during PCT.
Those that compete will appreciate proviron's hardening properties. Since proviron is 5-alpha reduced and not capable of forming estrogen, it will help give a drier look.
